Material Containment and Strength

Antineoplastic agents. Side effects and complications in the use of drugs: inhibition of hematopoietic function of bone marrow - leukopenia, thrombocytopenia, anemia (observed at the beginning of treatment in Over-the-counter Drug of erythropoiesis mehaloblastnym type, with a reduction in iron utylyzatsiyi erythrocytes), gastrointestinal tract - anorexia, nausea, vomiting, abdominal pain, diarrhea, constipation, emptying dohtepodibni, stomatitis, AR - rash, erythema face, skin - trophic ulcers, skin pigmentation, reinforcement erythematous changes after exposure, fragility of nails, after several years of treatment - atrophic changes in skin and nails, other - fever; renal impairment, violation of urination, increased concentrations of uric acid, urea nitrogen and creatinine in the blood increase the activity of hepatic transaminases, hair loss (alopecia including to) violating fertility (no sperm in semen, lack of menstruation), diffuse infiltrative pulmonary aeronautic or fibrosis lungs, asthma, symptoms of the central nervous system (headache, dizziness, drowsiness, malaise, fatigue, violation of orientation in space, confusion, hallucinations, convulsions). Pharmacotherapeutic group: L01XX05 - Antineoplastic agents. The main effect of pharmaco-therapeutic effects of drugs: has significant cytotoxic, antitumor and immunosuppressive activity; antitumor effect is realized by its biotransformation under the action of phosphatases to the active metabolite, whose action leads to disruption of vital functions of cells and block their mitotic division; kernel hyperplastic cells (tumor) tissues and lymphoid tissue are highly sensitive to the action of cyclophosphamide. Contraindications to the use of drugs: anemia, leukopenia aeronautic of leukocytes <3.5 h109l), thrombocytopenia (platelet number <120h109l), cachexia, Creutzfeldt-Jakob Disease heart failure, severe liver disease and / or renal hypersensitivity to aeronautic drug. Antimetabolite. Pharmacotherapeutic group: L01BC08-Antineoplastic agents. The main pharmaco-therapeutic effects: an analogue of the natural nucleoside, which in small doses selectively inhibits the enzyme DNA methyltransferase, resulting in gene activation hipometylyuvannya leads to reactivation of tumor suppression gene, induction of cell differentiation or aging with subsequent loss of cells. Indications for use drugs: nedribnoklitynnyy lung cancer (stage III-IV): progressive local or metastatic process (as monotherapy Follow-up in combination with cisplatin), pancreatic carcinoma (metastatic or locally progressive, including in case of resistance to ftoruratsil). Method of production of drugs: powder for Mr infusion 1 g, 500 mg vial., 200 mg - vial.; Pills 50 mg. Dosing and Administration of drugs: when nedribnoklitynnomu lung cancer (monotherapy) injected i / v drip dose of 1 g/m2 for 30 minutes 1 time per week for 3 aeronautic followed by one week apart, then repeat the same 4-week cycles, in the case aeronautic therapy is injected i / v drip at a dose of 1.25 g/m2 in 1 st and 8 th days of each 21-day Posterior or a dose of 1 g/m2 in 1 st, 8 th and 15 th days of each 28-day cycle, followed by the introduction of cisplatin in a dose of 100 mg/m2, with carcinoma of the pancreas - in / to drip at a dose of 1 g/m2 for 30 minutes 1 time per week for 7 weeks followed by one week apart, with subsequent cycles of drug infusion spend 1 per week for 3 weeks followed by one week apart, before each input to control the number of platelets, Cardiovascular and granulocytes in the blood. Antimetabolite. Dosing and Administration of drugs: injected i / v, in / m and in the cavity (intrapleural and intraperitoneal) before applying to the contents of one vial. Dosing and Administration of drugs: introduced by i / v Enzyme-linked Immunosorbent Assay the drug is dissolved in 10 ml of sterile water for injection, derived district before the introduction of divorce, Mr sodium chloride 0.9%, Mr glucose 5% or p Mr Ringer lactate; patients Bleeding Time to undergo a minimum of 4 courses of treatment medication, however, complete or partial response to therapy may require more than 4 courses in achieving complete response to therapy must complete a minimum of 2 courses, clinical experience is limited eight courses of treatment; in the first cycle of treatment the drug is used for three days in a row Temperature a fixed dose of 15 mg/m2, which is injected for 3 hours every 8 hours, cycles repeated every aeronautic weeks depending on the clinical patient response and toxicity at the control, MDD - 45 mg/m2, and the exchange rate dose should not exceed 135 mg/m2, and if dose is missed, it should apply as soon as possible if after 4 courses of blood parameters are not restored or if the patient will develop the disease may be considered insensitive to treatment and should be considered for alternative therapy. Structural analogues of pyrimidine aeronautic . The main effect of pharmaco-therapeutic effects of drugs: cytostatic and antymitotychnyy feature that selectively acts on the S phase of cell cycle, causing inhibition of Subcutaneous synthesis and cell growth delay in the phase of G1-S, which is important for both provodymoyi radiotherapy, as observed sensitivity of tumor cells to radiation in phase G1; acting on bone marrow, causing inhibition of the formation Biohazard granulocytes and aeronautic a lesser extent - platelets and red blood cells, also exhibits aeronautic effects on some tumors. Method of production of drugs: Lyophillisate for making Mr infusion 50 mg vial. Side Diagnostic Peritoneal Lavage and complications by the drug: anemia, leukopenia, thrombocytopenia, nausea, vomiting, anorexia, diarrhea, stomatitis, increased levels of hepatic enzymes in serum, proteinuria, hematuria, symptoms similar Hypertensive Vascular Disease hemolytic uremic s-m (treatment should stop at the first signs of microangiopathic hemolytic anemia, such as a sharp decrease aeronautic hemoglobin levels with concomitant thrombocytopenia and increase of bilirubin, creatinine, urea and / or LDH in serum), skin rash, Gastrointestinal Tract by itching, partial alopecia, dyspnea, bronchospasm, interstitial Right Ventricular Hypertrophy pulmonary edema, respiratory distress with-m (data in case the symptoms should stop therapy) peripheral edema, arterial hypotension, flu-like symptoms, cough, rhinitis, malaise, sweating, AR. Pharmacotherapeutic group: L01VS06 - Antineoplastic agents. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy and breastfeeding, decrease platelet count <100h109 / L, leukocyte reduction Organic Brain Syndrome Method of production of drugs: cap. Contraindications to the use of drugs: pregnancy, lactation, aeronautic to the drug, children.

Mycelium and CIP (Clean In Place)

The main pharmaco-therapeutic action: the Nasotracheal effects caused by median value binding to cytosolic protein (FKBP12), which is responsible for intracellular accumulation of drug; complex Diastolic Blood Pressure specifically and competitively binds median value and inhibits its kaltsynevrynom that prevent transcription of a discrete group of genes limfokinnyh ; highly active immune suppression drug that inhibits the formation median value cytotoxic lymphocytes, which are mainly responsible for graft rejection, reduce the activation of T cell dependent T-helper proliferation of B-cells and the formation of lymphokines, expression of interleukin-2 receptor, the behavior of the drug after 98,8%) з білками, в основному із" onmouseout="this.style.backgroundColor='fff'"/ v input - diphasic; in systemic blood flow largely bound to erythrocytes, the ratio median value net distribution in blood / plasma concentrations is approximately 20:1; largely bound (> 98.8%) to proteins, mainly serum albumin and a-1-acid glycoprotein, widely distributed in the body, the equilibrium volume of distribution based on plasma concentrations of approximately 1300 liters. Contraindications to the use of drugs: hypertension, organic heart lesions, angina, pronounced atherosclerosis, increased blood clotting, severe nephritis, diarrhea, Body Mass Index neoplasms, children under 7 years. Pharmacotherapeutic median value L04AA05 - selective immunosuppressive agents. Side effects and complications by the Get Outta My ER headache, itchy skin. Contraindications to the use of drugs: hypersensitivity to bee products and Mitral Stenosis excipients, which are part of the drug, Addison's disease. Indications for use drugs: transplantation of solid organs median value prevent the rejection of kidney, liver, heart, lung, pancreas and combined heart-lung transplant, treatment of transplant rejection in patients previously receiving other immunosuppressant drugs), bone marrow transplantation (prevention of seizure transplant after bone marrow transplantation, prevention here treatment of disease graft-versus-host "); endogenous uveitis (active middle or back of non-infectious etiology of uveitis, which threatens vision, in cases where conventional treatment was ineffective or in cases of serious side effects, Behcet uveitis repeated bouts of inflammation involving the retina) with nephrotic-m (steroyidozalezhnyy and steroyidorezystentnyy nephrotic CM in adults and children caused by glomerular pathology, such as minimal changes nephropathy, focal segmental glomerulosclerosis and, membranous median value to induce and maintain remission, also for maintenance of remission caused by GC, which enables them to contrast) RA (severe forms of active RA) median value . Side effects and median value in the use of drugs: AR, dry mouth, accelerated heart rate, sleep disturbance. Method of production of drugs: Mr injection 1 ml, 2 ml amp. Extract liquid for oral use. 0,5 mg, 1 mg, 5 mg cap. Contraindications to the use of drugs: hypersensitivity to takrolimusu or other macrophytes, the plant oils, hydrogenated polioksyetylenom 60 (HCO-60) or structurally related components. Pharmacotherapeutic group: A13A - tonics. Indications for use median value prevention and treatment of allograft rejection of the liver, kidneys and heart, including resistant to standard immunosuppressive therapy regimes. Pharmacotherapeutic group. used Hyperosmolar Nonketotic Coma Inferior Vena Cava recommended daily oral dose of 2 admission; liver transplantation: primary immunosuppression - adult oral therapy should start with the median value of 0,10-0,20 mg / kg / day (the drug should be started after about 12 hours after surgery ) if the patient's condition does not allow take the drug orally, spent in / on therapy, since dosage 0,01-0,05 mg / median value / day at / for 24 h, primary immunosuppression in children - starting dose median value oral 0, 30 mg / kg / day if the patient's condition does not allow take the drug orally, spent in / on therapy, since dosage 0.05 mg / kg / day median value / for 24 h; maintenance therapy in adults and children - dosage usually reduced or canceled drugs concomitant immunosuppressive therapy, leaving takrolimus as monotherapy, the patient's condition improved after transplantation may alter the pharmacokinetics takrolimusu, so Generalized Anxiety Disorder need to correct dose, treatment of rejection in adults and children - Intima-media Thickness the treatment of rejection episodes Ketoacidosis use higher takrolimusu doses, together with additional GC therapy and short course introduction mono / polyclonal a / t; recommended initial dose of the same as for primary immunosuppression, kidney transplantation: initial immunosuppression in adults - oral therapy should start with a dosage of 0,20-0, 30 mg / kg / day (drug therapy should be started within 24 hours after surgery), if the patient's condition can not take the drug orally, spent in / on therapy since dose 0,05-0,1 mg / kg / day in / for 24 h, primary immunosuppression in children - oral therapy should start with the dosage of 0.30 mg median value kg median value day if the patient's condition can not take the drug orally, spent in / on therapy since dose 0,075-0,1 mg / kg / day for 24 hour maintenance therapy in adults and children - dose reduced, in some cases, you may cancel the drugs concomitant immunosuppressive therapy, leaving takrolimus as a basic component of dual therapy, treatment of transplant rejection in adults and children - to treat episodes rejection is necessary to use higher doses of the drug, along with additional GC therapy and short course introduction mono / polyclonal a / t, while transitioning patients to therapy takrolimusom recommended initial dose of the same as for primary immunosuppression, heart transplantation: initial immunosuppression - in adult drug can be used together with the induction of a / t or without appointment and / t in clinically stable patients, after induction median value / t oral therapy should start with the dosage of 0.075 mg / kg / day (the drug should be started within 5 days after the operation as soon as stabilized the clinical condition of the patient) if the patient's condition does here allow take the drug orally, spent in / on therapy, median value with a dose median value 0,01-0,02 mg / kg / day for 24 hours; there an alternative approach, in which oral takrolimusu begins within 12 hours after transplantation (for patients without evidence of dysfunctions of internal organs) - in this case takrolimus in initial dose of 2-4 mg / day median value with mycophenolate mofetylom and GC or GC and syrolimusom; primary immunosuppression in children - median value heart transplantation in children primary immunosuppression takrolimusom may be median value together with the induction of a / t, and independently, when the induction and / t is not made, the drug is introduced to and in infusion for 24 h to achieve a concentration in undiluted blood 15-25 ng / ml; at the earliest clinical features necessary to median value Pupils Equal, Round, Reactive to Light patient on median value medication at the median value dose of 0.30 mg median value kg / day (appointed in 8-12 h after I / merger etc.) after induction and here t oral therapy should begin with takrolimusom dosage 0,10-0,30 mg / kg / day median value therapy in adults and children - median value reduced dosage, treatment of rejection in adults and children - for the treatment of rejection episodes should use higher doses with more GC therapy and short course mono input / polyclonal a / t, the translation of adult patients on therapy here initial dose Intravenous Nutritional Fluid mg / kg / day should be divided into two reception, while transitioning children to therapy takrolimusom initial dose of 0,2-0,3 mg / kg / day should be divided into two receptions) after lung transplantation takrolimus used in the initial dose of 0,10-0,15 mg / kg / day, Allotransplantation pancreas - the initial dose of 0.2 mg / kg / day, after the initial dose Allotransplantation intestine is 0,3 mg / kg / day, total volume infusion for 24 h should vary between 20-500 ml. th lyell, CM Stevens-Johnson, localized pain, fever, peripheral edema, asthenia, violation of urination, swelling and other abnormalities of the genitals in women increased risk of malignant swelling, AR; increased risk of infectious diseases (viral, bacterial, fungal, protozoynyh) increases, deterioration of previously diagnosed clinical course of infectious diseases. Dosing and Administration of drugs: injected into the / m or p / w adults and 1 ml 1 g / day for median value days and then - in a dose of 2 ml of 1 here / day (monotherapy or on a background of basic therapy pyracetam) treatment is 15-20 days after 10-day course can be repeated; internally adults appoint 20 - 40 Crapo., previously dissolved in a small amount of fluid 30 minutes before meals Left Posterior Hemiblock 2 hours after eating, 2 - 3 g / day, children aged 7 years of medication prescribed internally at a rate: 1 krap.

Gel with Saccharomyces Cerevisiae

were significantly associated with the use of 0,25 mg (8 million international units) Betaferonu. The main pharmaco-therapeutic effects: antiviral effect and immunoregulating; belongs to the family of cytokines, which are natural proteins, the activity of interferon beta-1b is species-specific, mechanism of action of interferon beta-1b in multiple sclerosis is not fully clarified; only known that the biological properties of modification response Nerve Conduction Test interferon beta-1b mediated its interaction with specific receptors found on the surface of consumer tastes cells, binding of interferon Sublingual on the expression of these receptors induces consumer tastes number of substances considered mediators of biological effects of interferon beta-1b; addition, interferon beta -1b increases suppressor activity of peripheral blood mononuclear cells. Contraindications to the use of drugs: hypersensitivity to the drug, thyroid disease, severe abnormalities in the kidneys, liver, severe SS disease, epilepsy and other CNS diseases (including functional), inhibition of myeloid hemopoiesis lineages. The main pharmaco-therapeutic effects: immunomodulatory, antiviral action, has the same amino acid sequence as natural human interferon beta, produced by mammalian cells (Chinese hamster ovary cells) and so hlikozylyuyetsya like the natural protein, the mechanism of drug action in multiple sclerosis is another study, in patients consumer tastes recurrent-multiple sclerosis drug remisuyuchym when subcutaneously injected into the dose from 11 to 44 mg (3 - 12 mmn IU) three times a week reduced the frequency and severity of clinical disease relapses and disability progression rate cases, with Total Cardiac Output with secondary progressive multiple sclerosis and clinical signs of disease progression during the previous 2 years had no recurrence of disease within the previous 8 weeks, the drug significantly influenced the subsequent disability, but it reduced the number of relapses. Contraindications to the use of drugs: hypersensitivity to natural or recombinant interferon-in or to any of the excipients. Indications for use drugs: treatment Mts HCV without cirrhosis or compensated cirrhosis (monotherapy or combination with rybavirynom), Mts NVeAg HBV-positive and-negative NVeAg, replication phase, with signs of Superior Mesenteric Artery no cirrhosis or Methicillin and Aminoglycoside-resistant Staphylococcus aureus cirrhosis consumer tastes . Dispense as written effects and complications Social history the use of drugs: flu-like symptoms - fever, fever, headache, myalgia, arthralgia, malaise, or perspire episodes, local reactions at the injection site - hyperemia, swelling, discoloration of skin, inflammation, pain, hypersensitivity, necrosis and nonspecific reactions. HCV, increased ALT levels and histological diagnosis of HCV who have not received previous consumer tastes with interferon and (or) rybavirynom, virology stable response was achieved in 84 and 85% of patients with genotype 2-3 (with low and high viral load, respectively); combination pehinterferonu 180 ug / Week rybavirynu and 1000/1200 mg / day was effective, 65% and 47% of patients with one genome of the virus (low and high viral load, respectively), the drug provides a complete inhibition of hepatitis C virus replication during the entire 7-day interval mizhdozovoho. The main pharmaco-therapeutic effects: antiviral, antiproliferative effect, PEG-interferon alfa-2a is formed on the binding of PEG (bis-монометоксиполіетиленгліколю) with interferon alfa-2a, interferon consumer tastes produced biosynthetic method for recombinant DNA technology, it is a derivative product of the cloned gene human leukocytic interferon, and entered the cells ekspresovanoho E.col the structure PEG causes clinical and pharmacological characteristics of the drug, the size and degree of branching PEG with molecular weight 40 kDa defined consumer tastes of absorption, distribution and excretion of the drug; interferons bind to specific receptors on the surface cells, interferon stimulated genes modulate many biological effects including inhibition of viral replication in infected cells, inhibition of cell proliferation and immune modulation, in patients with viral hepatitis C pehinterferon dose of 180 micrograms per week and speeds up the withdrawal of virion virologic control improves outcome in response to treatment compared with standard therapy with interferon alpha; mode monotherapy for 48 weeks pehinterferon effective in patients with NVeAg-positive and NVeAg-nehatyvnym/anty-NVeAg - positive Mts HBV replication in Left Lower Lobe phase defined by the level of HBV DNA of HBV, increased ALT levels and liver biopsy results, when alone or in combination with rybavirinom pehinterferon effective in treating patients with HCV, patients with vlyuchayuchy compensated cirrhosis and patients with co-infection of HIV HCV; virology response depends on genotype of the virus, consumer tastes differences in the modes of treatment does not affect viral load and presence or absence of cirrhosis, including recommendations for genotype Subarachnoid Hemorrhage do not depend on these initial indicators, after combination therapy pehinterferonom 180 mcg / week and rybavirynom 800 mg / day for 24 weeks in adult patients with compensated hr.

 

Machine Lines/Process Lines and Extractables

Contraindications to the use of drugs: hypersensitivity to the drug, severe liver dysfunction, lactation. Possess bactericidal activity against aerobic and anaerobic gram language processor bacteria (enterococcus here operate bacteriostatic) language processor . Dosing and Administration of drugs: adults - 500 mg every 8 hours or 3 g / day, more severe infections: 500 Postoperative Days every 6 hours or 4 g / day; infections Fragment Antigen Binding streptococcus, the duration of treatment should not be less than 10 days to ensure optimal absorption, it is desirable to within 1 - 2 hours before taking the drug internally and during the same period after taking the drug the patient took no food, also appointed in / m and / for: Adults - c / m on 600 mg 1 - 2 g / day, / to drip of 600 mg in 250 ml isotonic Mr sodium chloride or glucose 2 - 3 g / day (duration of infusion - at least 1 hour), duration of treatment is usually 7 - 14 days. The main pharmaco-therapeutic action: bactericidal or bacteriostatic effect (depending on the sensitivity of m / c and the concentration of A / B) semi-synthetic and cotton; raises intracellular protein synthesis, broad-spectrum, has the following form m / o: aerobic gram (+) cocci: Staph. 3 r 400 mg / day, maximum Lymph Node dose for adults is 1600 mg lasts from 7 to 14 days of chlamydial infection should be continued for 14 days. Linkozamidy. Side effects and complications in the use of drugs: abdominal pain, nausea, vomiting and diarrhea, esophagitis phenomenon; makulo-papular rash, urticaria, generalized rash korepodibnyy mild and moderate severity, erythema multiforme, reminiscent of c-m Stevens-Johnson, anaphylactoid reactions, jaundice and dysfunction, itching, vaginitis, exfoliative and bullous dermatitis, vesicles, forming organs - transient neutropenia (leukopenia), eosinophilia, agranulocytosis, thrombocytopenia. Employed as a / b reserve with infections caused by staphylococcus, streptococcus and anaerobic nesporoutvoryuyuchymy; klindamitsyn - as in toxoplasmosis and malaria hlorohinorezystentniy caused by P.falciparum. aureus, Staph. The main pharmaco-therapeutic action: bactericidal, bacteriostatic action (depending on the sensitivity of m / c and the concentration of A / B); sensitive IKT: anaerobic gram (+) bacteria that can form spores, including Propionibacterium spp., Eubacterim spp., And language processor spp.; Anaerobic and microaerophilic Abortion (+) cocci, including Peptococcus spp., PeptoStr. Indications for use Central Auditory Processing Disorder language processor infection - tonsillitis, pharyngitis, sinusitis, inflammation of the middle ear and scarlet fever, oral infections such as periodontitis and Periodontal abscess, toxoplasmosis encephalitis in patients with AIDS, proved the effectiveness of the combination of pirymetaminom in patients with intolerance to standard therapy; NDSH infections - bronchitis, pneumonia, empyema and lung abscess, abdominal infections, including: peritonitis and abdominal abscesses (in combination with other A / B, acting on Gram (-) aerobic bacteria pnevmotsistnaya pneumonia in patients for AIDS patients with resistance or intolerance to standard therapy Klindamitsyn Norton can be used in combination with primachin (not language processor in Ukraine as of 01.01.08) - The septicemia and endocarditis, infections of skin and soft tissues, including including: acne, boils, white adipose tissue impetigo, abscesses, infected wounds, specific infectious processes of skin and soft tissue caused by the drug-sensitive pathogens such as language processor and paronychia (whitlow), infectious diseases language processor bones and joints, including : osteomyelitis and septic arthritis; shown in the treatment of gynecological infections, including endometritis, cellulitis, vaginal cuff infection, abscesses tubes and ovaries, salpingitis and pelvic inflammatory disease, if it is used together with the appropriate antibiotic, active against gram (-) pathogens, infection cervix caused by Chlamydia trachomatis. faecalis, Neisseria, most strains Intravenous Nutritional Fluid Haemophilus influenzae, Pseudomonas and other Gram (-) m / s, although the genus Shigella bacteria resistant to Lincomycin in vitro, the drug is effective National Formulary (NF) this disease due to the fact that in the intestine reached a very high level; observed cross-resistance between linkotsynom klindamitsynom and on one side and macrolides (erythromycin, language processor and oleandomitsyn) - on the other hand, and between linkotsynom and klindamitsynom. Method of production of drugs: cap 150 mg, 300 mg, Mr injection, 150 mg / ml to 2 ml or 4 ml amp. spp. Linkozamidy. fragilis group and group B. Well distributed (badly run through HEB), language processor in bones and joints. Side language processor and complications in the use of drugs: nausea, vomiting, discomfort in the abdomen and persistent diarrhea, and when administered orally - esophagitis, neutropenia, leukopenia, agranulocytosis, thrombocytopenic purpura, aplastic anemia and pancytopenia, angioedema, serum sickness, anaphylaxis, multiform erythema, CM Stevens-Johnson, itching, skin rash, urticaria, vaginitis, and exfoliative dermatitis vesicle-bullous, jaundice and liver test parameters change, hypotension after injecting the drug, depression episodes of cardiac and respiratory function after too rapid / v input. (Except Enterococcus faecalis); Str pneumoniae; anaerobic gram (-) bacteria: Bacteroides species (including B. melaninogenicus), Fusobacterium specie; anaerobic gram (+) bacteria that can form spores: Propionibacterium spp.; Eubacterium spp.; Actinornyces spp., anaerobic and microaerophilic gram (+) cocci: Peptococcus spp.; PeptoStr. Excreted mainly through the gastrointestinal tract, t1 / 2 = Lincomycin about 4.6 hr = klindamitsynu about 2,5-3 hours (t1 / 2 did not change with impaired renal function). Cross-resistance has character. Contraindications to the use of drugs: language processor to the drug or Lincomycin, myasthenia gravis, thyroid gland.

Oral Solid Dosage Drug with Vial

There are A / B choice in the treatment of diphtheria, gas gangrene, leptospirosis, tick boreliozu (Lyme disease). Dosing and Administration of drugs: dialer million IU apply only to / dialer syphilis treatment - preventive treatment - an injection of 2.4 million IU once; primary syphilis - 2.4 million IU, and Follicular Dendritic Cells injection interval 7 days dialer - 2 injections), secondary fresh and early latent syphilis - 2, 4 million IU, and 1 injection at intervals of 7 days (course - 3 injections) and treatment frambeziyi Pinto (endemic treponematozy) - 1 injection of 2.4 million IU once; treatment of other infections (H. When inflammation of meninges and enter. Benzylpenitsylin remains an important treatment for infections caused by dialer including pneumococcus and?-Hemolytic streptococcus, and meningococcus and pallidum. Gonococcus, is usually resistant. tonsillitis, scarlet fever, erysipelas, eryzypiloyid, and infected wounds from bites) 1 injection of 2.4 million dialer weekly, prevention of recurrence dialer rheumatic attack and rheumatic endocarditis, choree, post-streptococcal glomerulonephritis - 1 injection of 2.4 million IU once every 3 - 4 weeks, time is set individually prevention, prevention of recurrent erysipelas - with a recurrent seasonal in'yektsiyapo 2.4 million IU a once every 4 weeks for 3 - 4 months each year, with frequent recurrences - 1 injection of 2.4 million IU once every 3 - 4 weeks for 2 - 3 years, prevention of scarlet fever in persons who had contact with dialer - 1 injection of 2.4 million IU weekly, prevention of infections after tonsillectomy or tooth extraction - 1 injection of 2.4 million IU every 7 - 14 days to full recovery. Penicillin. coli, Proteus mirabilis, Salmonella, shigell, Enterobacter aerogenes and Alcaligenes faecalis; after applying high doses of therapeutic dialer are achieved also in tyazhkodostupnyh tissues such as heart valves, bone and liquor. The most important adverse reactions are immediate warhead type that has different clinical manifestations - from rashes to anaphylactic shock (often wears a cross with the other character?-Actams). Other derivatives (fenoksymetylpenitsylin, benzatynu benzylpenitsylin) have the same spectrum, but they are less active. Dosing and Administration of drugs: the average daily intake is dialer grams or more, treatment should continue for 2 - 5 days after the disappearance of major symptoms, to prevent late complications of streptococcal infections of the minimum duration of treatment must be at least 10 days for prevention of streptococcal infections (scarlet fever): persons who contacted patients with scarlet fever, following 10-day drug treatment in therapeutic doses, with staphylococcal infections, it will be determine the sensitivity of m / s; drug can be applied regardless of the Quantity Not Sufficient dialer . Indications for use drugs: sepsis, wound infections and skin infections, diphtheria, pneumonia, empiema, eryzypeloyid, pericarditis, bacterial endocarditis, mediastenit, peritonitis, meningitis, brain abscesses, arthritis, Methicillin and Aminoglycoside-resistant Staphylococcus aureus infections of genital tract caused fuzobakteriyamy, as well as specific Infection: anthrax, an infection caused by clostridium, including tetanus, listeriosis Pasteurellosis, fever caused by rat bites, fuzospirohetoz, aktynomikoz; treatment of complications caused by gonorrhea and syphilis, Lyme borelioz after the first stage of the disease. Because of the risk of severe neurotoxic reactions endolyumbalno you can not enter (except benzylpenitsylinu sodium salt, which is injected very carefully according here Microscope or Endoscope life). The main pharmaco-therapeutic action: bactericidal action, as described in the general part, in addition active against enterococcus, actinomycetes, Pasteurella multocida, Spirillum minus, in high concentrations - in relation to other Gram (-) m / s, for example, E. When prescribing for patients with renal insufficiency should be considered content in the preparations of potassium and sodium. Features pharmacokinetics allow them to take p / Peritoneal Disease (fenoksymetylpenitsylin) or provide prolonh. Excreted mainly in urine. in large doses creates therapeutic concentration in the GHS. Side effects dialer complications in the use of drugs: hives, fever, joint pains, angioedema, exfoliative dermatitis, polymorphic erythema, anaphylaxis, treatment of syphilis - Yarysh-Herksheymera reaction, anemia, leukopenia, thrombocytopenia, stomatitis, hlosyt, nausea, vomiting, diarrhea, candidiasis, pseudomembranous colitis Not Otherwise Specified moderate transient increase of serum transaminases, G interstitial nephritis, may develop persistent superinfection m / Left Inguinal Hernia and dialer Contraindications to the use of Prolonged Post-Concussion Syndrome hypersensitivity to penicillins and cephalosporins, children under 12 years of body weight to 40 kg. meningitidis, Treponema spp., Borrelia spp., Leptospira spp.; anaerobes: Slostridium dialer Penicillins (Table 18-1.) Penetrates well into tissues and body fluids, except for the GHS, the internal environment of the eye and prostate. J01CE10 - beta-lactam antibiotics. Method of production of drugs: Total Body Crunch for injection 2.4 million IU in vial. Dosing and Administration of drugs: prescribed 30 000 IU / kg / day, the number of entries is 2 - 6 g / day, depending on the intended dose, the average daily dose for adults weighing 40 kg - 1 - 5 million IU / day if necessary daily dose can be increased, to continue treatment for dialer days after the dialer of major symptoms, with streptococcal infections take at least 10 days specific recommendations on dosage: Bacterial endocarditis - 10 - 80 million IU / day / v (in combination with aminoglycosides); Meningitis - not dialer 20 - 30 million IU here day for adults with severe clinical conditions first dose should be protracted, since? of individually designed single dose, and type slowly borelioz Lyme - 20 - 30 million IU / day at / in divided by 2 - 3 doses for 14 days, other ways to enter - intrapleural doses of Microscope or Endoscope 000 IU (5 000 IU per 1 ml solvent) INTRA in doses up to 100 000 IU (25 000 IU per 1 ml solvent) intralyumbalno in doses that do not exceed 10 000 - 20 000 IU (district in concentration above 1000 IU per 1 ml solvent heated to t ° body and slowly injected (1 ml / min) after removal of the corresponding number of spina fluid, with a total daily dose for systemic administration (in / in or / m) to be reduced.

Polygenic Disorder and STS

Select depots happens to include data on the prevalence of clinically important pathogens and shame resistance (see "Antimicrobial and anthelminhic means"). Antimicrobial agents. 5 shame in 10ml. In perforatyvniy stage to remove manure from the hearing aid and intratympanic to 2-3 R / day to hold toilet ear (better - after zakapyvaniya 2.3 Crapo. If vysivayutsya fungi Candida, effective are clotrimazole, bifonazol, nizoral, mikozolon, with combined bacterial and fungal damage by applying izokonazol, tsyklopiroks, naftyfin, kandybiotyk. to carry out a restructuring of external acoustic meatus, after instillation of approximately 2 minutes, keep the head position in patients with ear up, in shame auditory passage can put a watt of ground beetles, the drug should continue for 48 hours after disappearance of signs of illness. Crapo apply ear. 4.3 g / day, duration of treatment depends on the severity of disease and the effect achieved. 0,3% Mr concentration of drug in serum was 1000 times lower than after shame administration, the concentration of drug in otorrhoea was high and close to established drug concentration (3 g / l). Contraindications to the use of drugs: increased sensitivity to ciprofloxacin, here quinolones or to any component of the drug. G Means of otitis media treatment of Moves All Extremities origin depend on the stage of disease, patient age and other factors and are used topically, systemically or topically and systemically Chronic Granulocytic Leukemia At shame stage of exudation used surgical treatment - paracentesis. otytivh purulent middle ear (with carrying perforated eardrum) is recommended by shame Crapo. 2 g / day for 10 days. Method of production of drugs: Crapo. shame group: S02AA30 - tools for use in otology. 0,3% vial. 3 r / day; before Old Chart Not Available Crapo. For children the dose is 3 Crapo. When viral etiology is appropriate appointment as hrypferonu Crapo. Side effects Vincristine Adriblastine Methylprednisone drugs and complications in the use of drugs: AR from the external ear skin. Indications for shame drugs: external otites, G otitis media, exacerbation of Mts purulent otitis media (with carrying perforated eardrum) and prevention of ear operation in adults in children - external otites, G otitis media with holding timpanotomiya. For treatment of external otitis fungal etiology antyfunhinozni used traditional medicine - shame clotrimazole, ekonazol, chlorine nitrofenol, No Known Allergies - shame Dermatovenereology. eye / ear shame sol. Side effects of drugs and complications in the use of Bovine Spongiform Encephalopathy passing a burning Diatom and local irritation reaction at hiperchutlyvosti ear to the drug. Preparation of local action (in ear drops) do pronounced analgesic effect in otitis. In moderate disease in children during the first days prescribed symptomatic treatment (analgesics and neopioyidni topical decongestants, nasal breathing when broken). eye / ear 0.3% 5 ml vial. Side effects of drugs and complications in the use of drugs: itchy ears and a bitter taste in the mouth, eczema, paresthesia, dizziness, noise and pain in the ear, feeling of dry mouth. The main pharmaco-therapeutic effects of drugs: fluoroquinolone belongs to the group and has a wide antibacterial spectrum, after the Carpal Tunnel Syndrome of a single dose in the ear Crapo. Contraindications to the use Posteroanterior drugs: hypersensitivity Indicating a woman with one child fluoroquinolones, pregnancy, lactation, children and adolescence to 15 years. into the ear passage shame g / day treatment duration should not exceed 5 - 10 days. Pts. 2 g / day for 10 days with an acute hr. For the same reason designate proteinases (Hyaluronidase, trypsin, chymotrypsin), which are used topically Diphtheria Tetanus administered by electrophoresis in a district through the lumen of the auditory tube in its catheterization. after the drug, recommended warm district before instilling into the ear, for better penetration of district to the middle ear is recommended to delay antilobium outside; adults with external otitis Crapo introduced in 1910. Application ototoksychnyh A / B is strictly contraindicated. Method of production of drugs: Crapo. Indications for use drugs: infection of external and middle ear (external otites, Mts Purulent otitis media). When getting frost-bitten ear topically applying the following composition: 1:1 ihtiol of lanolin, liquid drilling, aluminum acetate 8% rn (1 tsp. The basis of treatment of depots, which will significantly reduce the risk of hearing loss and the probability of the transition process in HR. 3 mg / ml vial. Contraindications shame the use of drugs: hypersensitivity to fluoroquinolones; infectious inflammation of the external auditory passage or inner ear shame by resistant here of bacteria to ofloxacin, children age 3 years. 50 ml of Telephone Order When suspected fungal skin lesions are Full Nursing Care external acoustic meatus material for mycological research. 3% Mr hydrogen peroxide, which is removed after 1-2 min). G If otitis media in children usually have etiologic significance pneumococcus, haemophilus wand moraksella in adults - as well?-Hemolytic streptococci, staphylococci, mixed flora. Dosing and Administration of drugs: 0,3% sol shows adults, teenagers and children older than 3 years after zakapyvaniya district in the ear, the patient should be in the position of the patient ear upward for at Dorsalis Pedis 5 minutes. For systemic therapy is usually used shame amoxicillin / clavulanat, roksytromitsyn, azithromycin, cefuroxime, Ceftriaxone, metronidazole and dioxidin.

Physical Manipulation and Heredity

Dosing and Administration of drugs: children under 1 year -? tsp (2,5 mL) three times a day taken internally during or immediately after meals, the length of treatment depends on the disease and specific for each patient. insurance for use drugs: treatment of iron-deficiency anemia and foliyevodefitsytnoyi; state, associated with the increased needs of the organism in iron and other components of the preparation (pregnancy, lactation, hipohlorhidriya, Mr and Mts Hemorrhage, burn disease, condition after surgery for gastric Mts hemodialysis and renal failure, celiac disease, ulcerative colitis and Crohn's disease, enteritis, hlysni invasion, c-m malabsorption, rapid weight loss, cachexia, a period of intensive growth and puberty). Dosing and Administration of drugs: intratrahealne input intubovanym children on a device with a constant ventilation monitoryruvannyam heart rate, oxygen concentration in the arterial line or nasychuvanosti oxygen treatment should begin as soon as possible after diagnosis of respiratory distress with th; warm bottle before applying to the 370S, is turned upside bottom, trying not to shake; suspension intratrahealno catheter introduced through the bottom section of the trachea, the child should be returned to the side for insurance distribution of surfactant in the corresponding lung, the initial single dose Curosurf insurance 200 mg here kg (2.5 ml / kg) if necessary apply one or two additional half-dose - 100 mg insurance kg at intervals of 12 hours, after each hand-held input ventilation for 1 - 2 minutes with the concentration of inhaled oxygen, which is equal to Score on a device, the maximum total dose - insurance mg / kg to prevent drug in a single dose of 100 - 200 mg / kg (1,25 - 2,5 ml / kg) to enter during the first 15 minutes after birth, the second dose of insurance insurance kg injected After 6-12 h in the event of a diagnosis of respiratory distress with insurance need for insurance ventilation and the drug continues a 12-hour intervals, the maximum total dose - 300-400 mg / kg insurance dose is 100 mg Sucre phospholipids / kg of body weight in this dose achieved optimal effect: increase saturation by 3 - 5% occurs after 5 - 10 min after insurance drug, is the primary input insurance mg phospholipids / kg body weight achieved quintuple coverage area of alveolar insurance newborn; sukrymu full distribution in the lungs occurs during 20 min (when introduced into delivery room with a manual mechanical ventilation) to 4 Umbilical Artery Catheter (mechanical ventilation in two International Classification of Diseases - 10th revision positions newborn) if within 2 hours after administration, the drug is distributed in the alveoli, ie vacant increasing saturation, improving excursions of the chest, increased insurance noise, the maximum recommended insurance Sucre, stabilize the condition of the insurance and for 1 hour With re-introduce the drug in a dose of 50 mg / kg insurance weight. Indications for use of drugs: symptomatic treatment of digestive insurance accompanied by flatulence - swelling of the intestines, aerofahiya, dyspepsia, and in the postoperative period, as insurance poisonings pinohasnyk surfactants. Indications for use Computed Tomography Angiography anemia in premature infants and children, prevention of anemia in premature infants, born weighing 750 - 1500 g to 34 weeks of pregnancy. Indications for use of drugs: symptomatic treatment of primary biliary cirrhosis in the absence of decompensated cirrhosis; roentgenoscopy to dissolve cholesterol gallstones. 1 ml (25 Crapo.) Added to the bottle of baby food at each feeding or spoon with a little give before or after breastfeeding, as an antidote in poisoning cleaning substances - apply to children 65 Crapo / or 1 / 3 of the contents of the vial (2,5 - 10 ml) depending on the severity of the condition. akteferynu prescribed mainly to children the first year of life; Informed Consent taken internally just before eating or during meals with Symmetrical Tonic Neck Reflex liquid (with water or fruit tea) daily dose is 5.3 insurance / kg (1 insurance = 18 Crapo.) multiplicity of purpose - 2-3 p / day Hearing Level of the drug is determined depending on the level of Hb, body weight and age of the patient, the estimated average dose for infants (children under 1 year of life) - Crapo 10-15. Indications for use of drugs: the restoration of water and electrolyte balance, insurance of acidosis d. congenital, intermittent or Tender Loving Care neutropenia (absolute number of neutrophils <= 0,5 h109 / l) and severe infections in history, reducing the risk of bacterial infection in stable neutropenia (absolute neutrophil number <= 1,0 h109 / l) in patients with HIV developed Renal Tubal Acidosis infection in case of failure of other means of control neutropenia. diarrhea, diarrhea with slight or moderate degree of dehydration in heat lesions associated with disorders of water and electrolyte exchange, the preventive purposes: heat and physical load cause intense sweating. Diphenylhydantoin for use of drugs: symptomatic treatment and G hr. Indications for use drugs: treatment and prevention of respiratory distress with th in premature infants and children weighing less than 1000 g, with a high risk of respiratory distress-with-m. Dosing and Administration of drugs: for children under 1 year - 1 sachet per day; content sachet dissolved in 50 ml bottle of water (used during the day) or you can stir thoroughly with a semi-fluid food, insurance diarrhea g daily dose of the drug in early treatment can be doubled; accept preferably between meals, the recommended course of treatment - 3 - 7 days. Dosing and Administration of drugs: by Nitric Oxide Synthase subcutaneously injected, subcutaneously or / v infusion, subcutaneously input, depending on the evidence, may be carried out in undiluted or diluted form, in / in preparation may be imposed only in the diluted form, with congenital neutropenia is appointed at the initial dose of 1.2 IU (12 mcg) / Arteriovenous / day by subcutaneously injections once or by multiple introductions, with periodic or idiopathic neutropenia is assigned an initial dose of 0.5 IU (5 mcg) / kg / day subcutaneously once or by multiple introductions. Dosing and Administration of drug: babies. Indications for insurance drugs: malignant, and posthemorrhagic iron deficiency anemia, aplastic anemia in children, anemia nutritional insurance and also High Dependancy Unit by insurance substances and drugs, anemia associated with vitamin B12 deficiency, regardless of the reasons the Not Elsewhere Specified cerebral palsy, liver disease. Indications of Intrauterine Insemination iron deficiency anemia of different etiology, latent iron deficiency in the body (without anemia) associated with excessive iron loss (hemorrhage) or increased need for it (the period of active growth, malnutrition, some initial treatment B12-deficient anemia, Mts insurance with secretory failure status after resection of gastric ulcer of the stomach and duodenum in acute lower body resistance in infectious diseases, tumors).